Research Peptides · Cat. 052-05
PACAP 38 (Human, Rat, Ovine)
Supplied as 200 µg per unit. Purity ≥ 95%. Molecular weight 4534.32. Species: Human, Ovine, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 052-05 |
|---|---|
| Product type | Research Peptides |
| Peptide family | PACAP (Pituitary Adenylate Cyclase-Activating Polypeptide) |
| Species | Human, Ovine, Rat |
| Unit size | 200 µg |
| Molecular weight | 4534.32 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 200 µg of NET peptide. GalR3 activation promotes adult neural stem cell survival in response to a diabetic milieu. Mansouri S, Barde S, Ortsäter H, et al. J Neurochem. 2013;127(2):209-20. Western Blot Semi-Quantitative Analysis of Non-Canonical cAMP-Dependent Protein Expression Induced by PACAP. Jones E, Holighaus Y, Eiden L. CiteSeerx10M. 2013. Rapgef2 connects GPCR-mediated cAMP signals to ERK activation in neuronal and endocrine cells. Emery AC, Eiden MV, Mustafa T, Eiden LE. Sci Signal. 2013;6(281):ra51. Discrete signal transduction pathway utilization by a neuropeptide (PACAP) and a cytokine (TNF-alpha) first messenger in chromaffin cells, inferred from coupled transcriptome-promoter analysis of regulated gene cohorts. Samal B, Ait-ali D, Bunn S, Mustafa T, Eiden LE. Peptides. 2013;45:48-60. The hop cassette of the PAC1 receptor confers coupling to Ca2+ elevation required for pituitary adenylate cyclase-activating polypeptide-evoked neurosecretion. Mustafa T, Grimaldi M, Eiden LE. J Biol Chem. 2007;282(11):8079-91. Signaling mechanisms for alpha2-adrenergic inhibition of PACAP-induced growth hormone secretion and gene expression grass carp pituitary cells. Wang X, Chu MM, Wong AO. Am J Physiol Endocrinol Metab. 2007;292(6):E1750-62. Neuroprotection by endogenous and exogenous PACAP following stroke. Chen Y, Samal B, Hamelink CR, et al. Regul Pept. 2006;137(1-2):4-19. Vasoactive intestinal peptide and PACAP38 control N-methyl-D-aspartic acid-induced dendrite motility by modifying the activities of Rho GTPases and phosphatidylinositol 3-kinases. Henle F, Fischer C, Meyer DK, Leemhuis J. J Biol Chem. 2006;281(34):24955-69. Pituitary adenylate cyclase-activating polypeptide 27 is a functional ligand for formyl peptide receptor-like 1. Kim Y, Lee BD, Kim O, et al. J Immunol. 2006;176(5):2969-75. Secretin: hypothalamic distribution and hypothesized neuroregulatory role in autism. Welch MG, Keune JD, Welch-horan TB, et al. Cell Mol Neurobiol. 2004;24(2):219-41. Analysis of the PC12 cell transcriptome after differentiation with pituitary adenylate cyclase-activating polypeptide (PACAP). Vaudry D, Chen Y, Ravni A, Hamelink C, Elkahloun AG, Eiden LE. J Neurochem. 2002;83(6):1272-84. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
His-Ser-Asp-Gly-Ile-Phe-Thr-Asp-Ser-Tyr-Ser-Arg-Tyr-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-Tyr-Leu-Ala-Ala-Val-Leu-Gly-Lys-Arg-Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is PACAP 38 (Human, Rat, Ovine)?
What purity is listed for 052-05?
How should PACAP 38 (Human, Rat, Ovine) be stored?
What is the sequence of PACAP 38 (Human, Rat, Ovine)?
What is the intended use of 052-05?
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.