Research Peptides · Cat. 035-27
INSL3 / RLF (Human)
Supplied as 100 µg per unit. Purity ≥ 95%. Molecular weight 6292.32. Species: Human. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 035-27 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Insulin-Like Peptide 3 (INSL3) |
| Species | Human |
| Unit size | 100 µg |
| Molecular weight | 6292.32 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 100 µg of NET peptide. |
| B-Chain | Pro-Thr-Pro-Glu-Met-Arg-Glu-Lys-Leu-Cys-Gly-His-His-Phe-Val-Arg-Ala-Leu-Val-Arg-Val-Cys-Gly-Gly-Pro-Arg-Trp-Ser-Thr-Glu-Ala |
| Solubility | Soluble in water |
| Disulfide Bridge | Disulfide bridge(s): CysA10-CysA15, CysA11-CysB10, CysA24-CysB22 Cooperative binding of insulin-like Peptide 3 to a dimeric relaxin family peptide receptor 2. Svendsen AM, Vrecl M, Ellis TM, et al. Endocrinology. 2008;149(3):1113-20. The insulin-like growth factor type 1 and insulin-like growth factor type 2/mannose-6-phosphate receptors independently regulate ERK1/2 activity in HEK293 cells. El-shewy HM, Lee MH, Obeid LM, Jaffa AA, Luttrell LM. J Biol Chem. 2007;282(36):26150-7. The low-density lipoprotein class A module of the relaxin receptor (leucine-rich repeat containing G-protein coupled receptor 7): its role in signaling and trafficking to the cell membrane. Kern A, Agoulnik AI, Bryant-greenwood GD. Endocrinology. 2007;148(3):1181-94. T222P mutation of the insulin-like 3 hormone receptor LGR8 is associated with testicular maldescent and hinders receptor expression on the cell surface membrane. Bogatcheva NV, Ferlin A, Feng S, et al. Am J Physiol Endocrinol Metab. 2007;292(1):E138-44. Relaxin receptors in hepatic stellate cells and cirrhotic liver. Bennett RG, Dalton SR, Mahan KJ, Gentry-nielsen MJ, Hamel FG, Tuma DJ. Biochem Pharmacol. 2007;73(7):1033-40. Relaxin receptor expression in hepatic stellate cells and in cirrhotic rat liver tissue. Bennett RG, Mahan KJ, Gentry-nielsen MJ, Tuma DJ. Ann N Y Acad Sci. 2005;1041:185-9. Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7. Liu C, Chen J, Kuei C, et al. Mol Pharmacol. 2005;67(1):231-40. Mutation analysis of INSL3 and GREAT/LGR8 genes in familial cryptorchidism. Feng S, Cortessis VK, Hwang A, et al. Urology. 2004;64(5):1032-6. Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135. Liu C, Eriste E, Sutton S, et al. J Biol Chem. 2003;278(50):50754-64. Identification of relaxin-3/INSL7 as a ligand for GPCR142. Liu C, Chen J, Sutton S, et al. J Biol Chem. 2003;278(50):50765-70. GREAT/LGR8 is the only receptor for insulin-like 3 peptide. Bogatcheva NV, Truong A, Feng S, Engel W, Adham IM, Agoulnik AI. Mol Endocrinol. 2003;17(12):2639-46. |
| Research topics | Cancer Research |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Ala-Ala-Ala-Thr-Asn-Pro-Ala-Arg-Tyr-Cys-Cys-Leu-Ser-Gly-Cys-Thr-Gln-Gln-Asp-Leu-Leu-Thr-Leu-Cys-Pro-Tyr
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is INSL3 / RLF (Human)?
INSL3 / RLF (Human) is a research peptide listed under catalog number 035-27 in the Insulin-Like Peptide 3 (INSL3) family, human sequence. It is supplied as 100 µg per unit for in vitro laboratory research.
What purity is listed for 035-27?
The imported catalog record lists ≥ 95% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should INSL3 / RLF (Human) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of INSL3 / RLF (Human)?
The 26-residue sequence is Ala-Ala-Ala-Thr-Asn-Pro-Ala-Arg-Tyr-Cys-Cys-Leu-Ser-Gly-Cys-Thr-Gln-Gln-Asp-Leu-Leu-Thr-Leu-Cys-Pro-Tyr, molecular weight 6292.32.
What is the intended use of 035-27?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.