All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy.
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Agouti-Related Peptide (AgRP) — frequently asked
What is agouti-related peptide?
AgRP is a hypothalamic peptide related to agouti signalling protein. Its C-terminal cystine-knot region carries the activity described in the literature, which is why research catalogs list numbered fragments such as AgRP (83-132) rather than only the full-length sequence.
Why is AgRP researched?
AgRP is reported to antagonise melanocortin MC3 and MC4 receptors, opposing alpha-MSH signalling. Rodent studies associate AgRP-expressing arcuate neurons with feeding drive and body weight regulation, making the peptide a common tool in energy balance and receptor pharmacology research.
Which fragments and species are offered?
Human and mouse fragments are the most widely catalogued, along with agouti signalling protein sequences. Options include amidated C-terminal fragments, shorter N-terminal regions, and biotinylated or antibody-conjugated forms used for detection, pull-down and immunoassay work.
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