Polyclonal Antibodies · Antiserum · Cat. H-003-53
Agouti-Related Peptide (AgRP) (83-132) amide (Human) – Antibody
Supplied as 50 µl per unit. Species: Human. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | H-003-53 |
|---|---|
| Product type | Polyclonal Antibodies · Antiserum |
| Peptide family | Agouti-Related Peptide (AgRP) |
| Species | Human |
| Unit size | 50 µl |
| Contents | Each vial contains 50 µl of lyophilized rabbit antiserum. |
| Solubility | Reconstitute with 50 µl of distilled water for the equivalent of undiluted antiserum. |
| Source / Species | Rabbit Cocaine- and amphetamine-regulated transcript (CART) is colocalized with the orexigenic neuropeptide Y and agouti-related protein and absent from the anorexigenic alpha-melanocyte-stimulating hormone neurons in the infundibular nucleus of the human hypothalamus. Menyhért J, Wittmann G, Lechan RM, Keller E, Liposits Z, Fekete C. Endocrinology. 2007;148(9):4276-81. Hypothalamic proopiomelanocortin (POMC) neurons have a cholinergic phenotype. Meister B, Gömüç B, Suarez E, Ishii Y, Dürr K, Gillberg L. Eur J Neurosci. 2006;24(10):2731-40. Expression of agouti-related protein (AgRP) in the hypothalamus and adrenal gland of the duck ( Anas platyrhynchos). Mirabella N, Esposito V, Squillacioti C, De luca A, Paino G. Anat Embryol. 2004;209(2):137-41. Origin of neuropeptide Y-containing afferents to gonadotropin-releasing hormone neurons in male mice. Turi GF, Liposits Z, Moenter SM, Fekete C, Hrabovszky E. Endocrinology. 2003;144(11):4967-74. Hypothalamic NPY and agouti-related protein are increased in human illness but not in Prader-Willi syndrome and other obese subjects. Goldstone AP, Unmehopa UA, Bloom SR, Swaab DF. J Clin Endocrinol Metab. 2002;87(2):927-37. Hypophysiotropic thyrotropin-releasing hormone-synthesizing neurons in the human hypothalamus are innervated by neuropeptide Y, agouti-related protein, and alpha-melanocyte-stimulating hormone. Mihály E, Fekete C, Tatro JB, Liposits Z, Stopa EG, Lechan RM. J Clin Endocrinol Metab. 2000;85(7):2596-603. alpha-Melaanocyte-stimulating hormone is contained in nerve terminals innervating thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and prevents fasting-induced suppression of prothyrotropin-releasing hormone gene expression. Fekete C, Légrádi G, Mihály E, et al. J Neurosci. 2000;20(4):1550-8. Characterization of the neuroanatomical distribution of agouti-related protein immunoreactivity in the rhesus monkey and the rat. Haskell-luevano C, Chen P, Li C, et al. Endocrinology. 1999;140(3):1408-15. |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Storage & handling
Please store the lyophilized antibody at -20°C upon receipt for up to 24 months. For optimal results, use the antibody immediately after reconstitution. Once reconstituted, the antibody is stable for up to three (3) days at 4°C. For longer-term storage up to three (3) months, prepare small aliquots of the reconstituted antibody and freeze at -20°C or -80°C. Repeated freeze-thaw cycles should be strictly avoided.
Frequently asked
What is Agouti-Related Peptide (AgRP) (83-132) amide (Human) – Antibody?
Agouti-Related Peptide (AgRP) (83-132) amide (Human) – Antibody is a antiserum polyclonal antibodie listed under catalog number H-003-53 in the Agouti-Related Peptide (AgRP) family, human sequence. It is supplied as 50 µl per unit for in vitro laboratory research.
How should Agouti-Related Peptide (AgRP) (83-132) amide (Human) – Antibody be stored?
Please store the lyophilized antibody at -20°C upon receipt for up to 24 months. For optimal results, use the antibody immediately after reconstitution. Once reconstituted, the antibody is stable for up to three (3) days at 4°C. For longer-term storage up to three (3) months, prepare small aliquots of the reconstituted antibody and freeze at -20°C or -80°C. Repeated freeze-thaw cycles should be strictly avoided.
What is the intended use of H-003-53?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.