Research Peptides · Cat. 035-62
Relaxin 2 (Human) – 20µg
Supplied as 20 µg per unit. Purity ≥ 95%. Molecular weight 5963.06. Species: Human. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 035-62 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Relaxin |
| Species | Human |
| Unit size | 20 µg |
| Molecular weight | 5963.06 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 20 µg of NET peptide. |
| B-Chain | Asp-Ser-Trp-Met-Glu-Glu-Val-Ile-Lys-Leu-Cys-Gly-Arg-Glu-Leu-Val-Arg-Ala-Gln-Ile-Ala-Ile-Cys-Gly-Met-Ser-Thr-Trp-Ser |
| Solubility | Soluble in water |
| Disulfide Bridge | Disulfide bridge(s): CysA10-CysA15, CysA11-CysB11, CysA24-CysB23 Relaxin in paraventricular nucleus contributes to sympathetic overdrive and hypertension via PI3K-Akt pathway. Sun HJ, Chen D, Han Y, et al. Neuropharmacology. 2016;103:247-56. H2 and H3 relaxin inhibit high glucose-induced apoptosis in neonatal rat ventricular myocytes. Zhang X, Ma X, Zhao M, et al. Biochimie. 2015;108:59-67. Relaxin affects cell organization and early and late stages of spermatogenesis in a coculture of rat testicular cells. Pimenta MT, Francisco RA, Silva RP, Porto CS, Lazari MF. Andrology. 2015;3(4):772-86. Mesangial cells cultured from pregnant rats display reduced reactivity to angiotensin II: the role of relaxin, nitric oxide and AT2 receptor. Carvalho LN, Cristovam PC, Passos CS, Boim MA. Cell Physiol Biochem. 2012;30(6):1456-64. The positive inotropic effect of relaxin-2 in human atrial myocardium is preserved in end-stage heart failure: role of G(i)-phosphoinositide-3 kinase signaling. Dschietzig T, Alexiou K, Kinkel HT, Baumann G, Matschke K, Stangl K. J Card Fail. 2011;17(2):158-66. Relaxin stimulates osteoclast differentiation and activation. Ferlin A, Pepe A, Facciolli A, Gianesello L, Foresta C. Bone. 2010;46(2):504-13. Autoregulation of human relaxin-2 gene expression critically involves relaxin and glucocorticoid receptor binding to glucocorticoid response half-sites in the relaxin-2 promoter. Dschietzig T, Bartsch C, Wessler S, Baumann G, Stangl K. Regul Pept. 2009;155(1-3):163-73. |
| Research topics | Cardiovascular Research |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
pGlu-Leu-Tyr-Ser-Ala-Leu-Ala-Asn-Lys-Cys-Cys-His-Val-Gly-Cys-Thr-Lys-Arg-Ser-Leu-Ala-Arg-Phe-Cys
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is Relaxin 2 (Human) – 20µg?
What purity is listed for 035-62?
How should Relaxin 2 (Human) – 20µg be stored?
What is the sequence of Relaxin 2 (Human) – 20µg?
What is the intended use of 035-62?
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.