Research Peptides · Cat. 043-01
MSH, alpha (Human, Rat, Mouse)
Supplied as 500 µg per unit. Purity ≥ 96%. Molecular weight 1664.91. Species: Human, Mouse, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 043-01 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Melanocyte-Stimulating Hormone (MSH) |
| Species | Human, Mouse, Rat |
| Unit size | 500 µg |
| Molecular weight | 1664.91 Da |
| Purity | ≥ 96% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 500 µg of NET peptide. Functional characterization of nine novel naturally occurring human melanocortin-3 receptor mutations. Yang F, Tao YX. Biochim Biophys Acta. 2012;1822(11):1752-61. Refeeding-activated glutamatergic neurons in the hypothalamic paraventricular nucleus (PVN) mediate effects of melanocortin signaling in the nucleus tractus solitarius (NTS). Singru PS, Wittmann G, Farkas E, Zséli G, Fekete C, Lechan RM. Endocrinology. 2012;153(8):3804-14. Alpha-melanocyte stimulating hormone and ghrelin: central interaction in feeding control. Olszewski PK, Bomberg EM, Grace MK, Levine AS. Peptides. 2007;28(10):2084-9. Functional interaction between nociceptin/orphanin FQ and alpha-melanocyte-stimulating hormone in the regulation of feeding. Bomberg EM, Grace MK, Levine AS, Olszewski PK. Peptides. 2006;27(7):1827-34. PC1/3 and PC2 gene expression and post-translational endoproteolytic pro-opiomelanocortin processing is regulated by photoperiod in the seasonal Siberian hamster (Phodopus sungorus). Helwig M, Khorooshi RM, Tups A, et al. J Neuroendocrinol. 2006;18(6):413-25. C-terminal part of AgRP stimulates insulin secretion through calcium release in pancreatic beta Rin5mf cells. Kim HS, Yumkham S, Lee HY, et al. Neuropeptides. 2005;39(4):385-93. Alpha-melanocyte stimulating hormone protects against H2O2-induced inhibition of wound restitution in IEC-6 cells via a Syk kinase- and NF-kappabeta-dependent mechanism. Zou L, Sato N, Kone BC. Shock. 2004;22(5):453-9. Suppression of melanogenesis by induction of endogenous intracellular metallothionein in human melanocytes. Sasaki M, Kizawa K, Igarashi S, Horikoshi T, Uchiwa H, Miyachi Y. Exp Dermatol. 2004;13(8):465-71. Gain-of-function somatic cell lines for drug discovery applications generated by homologous recombination. Zeh K, Sanders P, Londo P, Crute JJ, Pollok BA, Whitney MA. Assay Drug Dev Technol. 2003;1(6):755-65. Effects of melanogenesis-inducing nitric oxide and histamine on the production of eumelanin and pheomelanin in cultured human melanocytes. Lassalle MW, Igarashi S, Sasaki M, Wakamatsu K, Ito S, Horikoshi T. Pigment Cell Res. 2003;16(1):81-4. Effects of melanocortin receptor ligands on thyrotropin-releasing hormone release: evidence for the differential roles of melanocortin 3 and 4 receptors. Kim MS, Small CJ, Russell SH, et al. J Neuroendocrinol. 2002;14(4):276-82. Identification of receptors for neuromedin U and its role in feeding. Howard AD, Wang R, Pong SS, et al. Nature. 2000;406(6791):70-4. Reduced abundance of aquaporins in rats with bilateral ischemia-induced acute renal failure: prevention by alpha-MSH. Kwon TH, Frøkiaer J, Fernández-llama P, Knepper MA, Nielsen S. Am J Physiol. 1999;277(3 Pt 2):F413-27. Alpha-melanocyte-stimulating hormone protects against renal injury after ischemia in mice and rats. Chiao H, Kohda Y, Mcleroy P, Craig L, Housini I, Star RA. J Clin Invest. 1997;99(6):1165-72. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is MSH, alpha (Human, Rat, Mouse)?
MSH, alpha (Human, Rat, Mouse) is a research peptide listed under catalog number 043-01 in the Melanocyte-Stimulating Hormone (MSH) family, human / mouse / rat sequence. It is supplied as 500 µg per unit for in vitro laboratory research.
What purity is listed for 043-01?
The imported catalog record lists ≥ 96% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should MSH, alpha (Human, Rat, Mouse) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of MSH, alpha (Human, Rat, Mouse)?
The 15-residue sequence is Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2, molecular weight 1664.91.
What is the intended use of 043-01?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.