ELISA / EIA / RIA Kits · RIA kit · Cat. RK-043-01
MSH, alpha (Human, Rat, Mouse) – RIA Kit
Supplied as 125 tubes per unit. Species: Human, Mouse, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | RK-043-01 |
|---|---|
| Product type | ELISA / EIA / RIA Kits · RIA kit |
| Peptide family | Melanocyte-Stimulating Hormone (MSH) |
| Species | Human, Mouse, Rat |
| Unit size | 125 tubes |
| Sensitivity | 82.8 pg/ml |
| Specificity | Peptide %ty a-MSH 100 b-MSH (Human) 0 g-MSH (Human) 0 ACTH (Human) 0 b-Endorphin (Human) 0 Met-Enkephalin 0 |
| Radioactivity | Each kit contains 1.5 µCi of Iodine 125. |
| Inter-Assay CV | <15% |
| Intra-Assay CV | <10% |
| Standard Curve | Contact us for technical specifications on this product. This package conforms to the 49 CFR173.421 for expected radioactive material limited quantity, N.O.S. UN2910. Dynamic modulation of prohormone convertase 2 (PC2)-mediated precursor processing by 7B2 protein: preferential effect on glucagon synthesis. Helwig M, Lee SN, Hwang JR, Ozawa A, Medrano JF, Lindberg I. J Biol Chem. 2011;286(49):42504-13. Obese carboxypeptidase E knockout mice exhibit multiple defects in peptide hormone processing contributing to low bone mineral density. Cawley NX, Yanik T, Woronowicz A, Chang W, Marini JC, Loh YP. Am J Physiol Endocrinol Metab. 2010;299(2):E189-97. AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons. Claret M, Smith MA, Batterham RL, et al. J Clin Invest. 2007;117(8):2325-36. Lean rats with hypothalamic pro-opiomelanocortin overexpression exhibit greater diet-induced obesity and impaired central melanocortin responsiveness. Li G, Zhang Y, Cheng KY, Scarpace PJ. Diabetologia. 2007;50(7):1490-9. Melanocortin activation of nucleus of the solitary tract avoids anorectic tachyphylaxis and induces prolonged weight loss. Li G, Zhang Y, Rodrigues E, et al. Am J Physiol Endocrinol Metab. 2007;293(1):E252-8. Plasma and hypothalamic peptide-hormone levels regulating somatotroph function and energy balance in fed and fasted states: a comparative study in four strains of rats. Kappeler L, Zizzari P, Grouselle D, Epelbaum J, Bluet-pajot MT. J Neuroendocrinol. 2004;16(12):980-8. Proopiomelanocortin-derived peptides in rat cerebrospinal fluid and hypothalamic extracts: evidence that secretion is regulated with respect to energy balance. Pritchard LE, Oliver RL, Mcloughlin JD, et al. Endocrinology. 2003;144(3):760-6. Obliteration of alpha-melanocyte-stimulating hormone derived from POMC in pituitary and brains of PC2-deficient mice. Miller R, Aaron W, Toneff T, Vishnuvardhan D, Beinfeld MC, Hook VY. J Neurochem. 2003;86(3):556-63. ARC POMC mRNA and PVN alpha-MSH are lower in obese relative to lean zucker rats. Kim EM, O'hare E, Grace MK, Welch CC, Billington CJ, Levine AS. Brain Res. 2000;862(1-2):11-6. STZ-induced diabetes decreases and insulin normalizes POMC mRNA in arcuate nucleus and pituitary in rats. Kim EM, Grace MK, Welch CC, Billington CJ, Levine AS. Am J Physiol. 1999;276(5 Pt 2):R1320-6. Changes in hypothalamic agouti-related protein (AGRP), but not alpha-MSH or pro-opiomelanocortin concentrations in dietary-obese and food-restricted rats. Harrold JA, Williams G, Widdowson PS. Biochem Biophys Res Commun. 1999;258(3):574-7. |
| Standard Range | 10 - 1280 pg/ml |
| Sample Extraction | Recommended |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Frequently asked
What is MSH, alpha (Human, Rat, Mouse) – RIA Kit?
MSH, alpha (Human, Rat, Mouse) – RIA Kit is a ria kit elisa / eia / ria kit listed under catalog number RK-043-01 in the Melanocyte-Stimulating Hormone (MSH) family, human / mouse / rat sequence. It is supplied as 125 tubes per unit for in vitro laboratory research.
What is the intended use of RK-043-01?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.