Research Peptides · Cat. 048-59
KiSS-1 (68-121) amide / Kisspeptin-54 / Metastin (1-54) amide (Human)
Supplied as 100 µg per unit. Purity ≥ 96%. Molecular weight 5857.51. Species: Human. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 048-59 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Kisspeptin (KiSS-1 / Metastin) |
| Species | Human |
| Unit size | 100 µg |
| Molecular weight | 5857.51 Da |
| Purity | ≥ 96% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 100 µg of NET peptide. Immunohistochemical evidence for the presence of various kisspeptin isoforms in the mammalian brain. Franceschini I, Yeo SH, Beltramo M, et al. J Neuroendocrinol. 2013;25(9):839-51. Presence of kisspeptin-like immunoreactivity in human adrenal glands and adrenal tumors. Takahashi K, Shoji I, Shibasaki A, et al. J Mol Neurosci. 2010;41(1):138-44. Studies of the localisation of kisspeptin within the pituitary of the rhesus monkey (Macaca mulatta) and the effect of kisspeptin on the release of non-gonadotropic pituitary hormones. Ramaswamy S, Gibbs RB, Plant TM. J Neuroendocrinol. 2009;21(10):795-804. An increase in kisspeptin-54 release occurs with the pubertal increase in luteinizing hormone-releasing hormone-1 release in the stalk-median eminence of female rhesus monkeys in vivo. Keen KL, Wegner FH, Bloom SR, Ghatei MA, Terasawa E. Endocrinology. 2008;149(8):4151-7. Sex steroids and leptin regulate the "first Kiss" (KiSS 1/G-protein-coupled receptor 54 system) in human gonadotropin-releasing-hormone-secreting neuroblasts. Morelli A, Marini M, Mancina R, et al. J Sex Med. 2008;5(5):1097-113. Expression of a functional g protein-coupled receptor 54-kisspeptin autoregulatory system in hypothalamic gonadotropin-releasing hormone neurons. Quaynor S, Hu L, Leung PK, et al. Mol Endocrinol. 2007;21(12):3062-70. The role of kisspeptin-GPR54 signaling in the tonic regulation and surge release of gonadotropin-releasing hormone/luteinizing hormone. Dungan HM, Gottsch ML, Zeng H, et al. J Neurosci. 2007;27(44):12088-95. The kisspeptin receptor GPR54 is required for sexual differentiation of the brain and behavior. Kauffman AS, Park JH, Mcphie-lalmansingh AA, et al. J Neurosci. 2007;27(33):8826-35. A role for kisspeptins in the regulation of gonadotropin secretion in the mouse. Gottsch ML, Cunningham MJ, Smith JT, et al. Endocrinology. 2004;145(9):4073-7. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Gly-Thr-Ser-Leu-Ser-Pro-Pro-Pro-Glu-Ser-Ser-Gly-Ser-Arg-Gln-Gln-Pro-Gly-Leu-Ser-Ala-Pro-His-Ser-Arg-Gln-Ile-Pro-Ala-Pro-Gln-Gly-Ala-Val-Leu-Val-Gln-Arg-Glu-Lys-Asp-Leu-Pro-Asn-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is KiSS-1 (68-121) amide / Kisspeptin-54 / Metastin (1-54) amide (Human)?
What purity is listed for 048-59?
How should KiSS-1 (68-121) amide / Kisspeptin-54 / Metastin (1-54) amide (Human) be stored?
What is the sequence of KiSS-1 (68-121) amide / Kisspeptin-54 / Metastin (1-54) amide (Human)?
What is the intended use of 048-59?
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.