Research Peptides · Cat. 048-56
KiSS-1 (112-121) amide / Kisspeptin-10 / Metastin (45-54) amide (Human)
Supplied as 200 µg per unit. Purity ≥ 95%. Molecular weight 1302.44. Species: Human. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 048-56 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Kisspeptin (KiSS-1 / Metastin) |
| Species | Human |
| Unit size | 200 µg |
| Molecular weight | 1302.44 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 200 µg of NET peptide. Intratesticular action of kisspeptin in rhesus monkey (Macaca mulatta). Irfan S, Ehmcke J, Wahab F, Shahab M, Schlatt S. Andrologia. 2014;46(6):610-7. FGF21 contributes to neuroendocrine control of female reproduction. Owen BM, Bookout AL, Ding X, et al. Nat Med. 2013;19(9):1153-6. Evidence for a celiac ganglion-ovarian kisspeptin neural network in the rat: intraovarian anti-kisspeptin delays vaginal opening and alters estrous cyclicity. Ricu MA, Ramirez VD, Paredes AH, Lara HE. Endocrinology. 2012;153(10):4966-77. Kisspeptin acts directly and indirectly to increase gonadotropin-releasing hormone neuron activity and its effects are modulated by estradiol. Pielecka-fortuna J, Chu Z, Moenter SM. Endocrinology. 2008;149(4):1979-86. Direct kisspeptin-10 stimulation on luteinizing hormone secretion from bovine and porcine anterior pituitary cells. Suzuki S, Kadokawa H, Hashizume T. Anim Reprod Sci. 2008;103(3-4):360-5. Neuroendocrine phenotype analysis in five patients with isolated hypogonadotropic hypogonadism due to a L102P inactivating mutation of GPR54. Tenenbaum-rakover Y, Commenges-ducos M, Iovane A, Aumas C, Admoni O, De roux N. J Clin Endocrinol Metab. 2007;92(3):1137-44. Environmental control of kisspeptin: implications for seasonal reproduction. Greives TJ, Mason AO, Scotti MA, et al. Endocrinology. 2007;148(3):1158-66. Suppression of kisspeptin expression and gonadotropic axis sensitivity following exposure to inhibitory day lengths in female Siberian hamsters. Mason AO, Greives TJ, Scotti MA, et al. Horm Behav. 2007;52(4):492-8. Characteristic of hypothalamic kisspeptin expression in the pubertal development of precocious female rats. Sun Y, Tian Z, Zhao H, Wong ST, Chen B. Neurosci Lett. 2007;420(1):12-7. Colocalization of kisspeptin and gonadotropin-releasing hormone in the ovine brain. Pompolo S, Pereira A, Estrada KM, Clarke IJ. Endocrinology. 2006;147(2):804-10. Expression of hypothalamic KiSS-1 system and rescue of defective gonadotropic responses by kisspeptin in streptozotocin-induced diabetic male rats. Castellano JM, Navarro VM, Fernández-fernández R, et al. Diabetes. 2006;55(9):2602-10. Cancer metastasis-suppressing peptide metastin upregulates excitatory synaptic transmission in hippocampal dentate granule cells. Arai AC, Xia YF, Suzuki E, Kessler M, Civelli O, Nothacker HP. J Neurophysiol. 2005;94(5):3648-52. Two novel missense mutations in g protein-coupled receptor 54 in a patient with hypogonadotropic hypogonadism. Semple RK, Achermann JC, Ellery J, et al. J Clin Endocrinol Metab. 2005;90(3):1849-55. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is KiSS-1 (112-121) amide / Kisspeptin-10 / Metastin (45-54) amide (Human)?
KiSS-1 (112-121) amide / Kisspeptin-10 / Metastin (45-54) amide (Human) is a research peptide listed under catalog number 048-56 in the Kisspeptin (KiSS-1 / Metastin) family, human sequence. It is supplied as 200 µg per unit for in vitro laboratory research.
What purity is listed for 048-56?
The imported catalog record lists ≥ 95% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should KiSS-1 (112-121) amide / Kisspeptin-10 / Metastin (45-54) amide (Human) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of KiSS-1 (112-121) amide / Kisspeptin-10 / Metastin (45-54) amide (Human)?
The 11-residue sequence is Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2, molecular weight 1302.44.
What is the intended use of 048-56?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.