Research Peptides · Cat. 061-05
Substance P (Human, Rat, Mouse)
Supplied as 500 µg per unit. Purity ≥ 95%. Molecular weight 1347.65. Species: Human, Mouse, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 061-05 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Substance P & Tachykinins |
| Species | Human, Mouse, Rat |
| Unit size | 500 µg |
| Molecular weight | 1347.65 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 500 µg of NET peptide. Investigation of the metabolic biotransformation of substance P in liver microsomes by liquid chromatography quadrupole ion trap mass spectrometry. Pailleux F, Lemoine J, Beaudry F. Biomed Chromatogr. 2013;27(1):39-47. Alleviation of chronic neuropathic pain by environmental enrichment in mice well after the establishment of chronic pain. Vachon P, Millecamps M, Low L, et al. Behav Brain Funct. 2013;9:22. Targeted liquid chromatography quadrupole ion trap mass spectrometry analysis of tachykinin related peptides reveals significant expression differences in a rat model of neuropathic pain. Pailleux F, Vachon P, Lemoine J, Beaudry F. Neuropeptides. 2013;47(4):261-71. Quantitative mass spectrometry analysis reveals that deletion of the TRPV1 receptor in mice alters substance P and neurokinin A expression in the central nervous system. Pailleux F, Lemoine J, Beaudry F. Neurochem Res. 2012;37(12):2678-85. Early dexamethasone treatment after implantation of a sciatic-nerve cuff decreases the concentration of substance P in the lumbar spinal cord of rats with neuropathic pain. Beaudry F, Girard C, Vachon P. Can J Vet Res. 2007;71(2):90-7. Substance P receptor expression in healthy and inflamed human pulp tissue. Caviedes-bucheli J, Gutierrez-guerra JE, Salazar F, Pichardo D, Moreno GC, Munoz HR. Int Endod J. 2007;40(2):106-11. Determination of substance P in rat spinal cord by high-performance liquid chromatography electrospray quadrupole ion trap mass spectrometry. Beaudry F, Vachon P. Biomed Chromatogr. 2006;20(12):1344-50. Adrenomedullin is a cross-talk molecule that regulates tumor and mast cell function during human carcinogenesis. Zudaire E, Martínez A, Garayoa M, et al. Am J Pathol. 2006;168(1):280-91. Tachykinin agonists modulate cholinergic neurotransmission at guinea-pig intracardiac Ganglia. Zhang L, Hancock JC, Hoover DB. J Pharmacol Sci. 2005;99(3):228-38. Hemokinin-1 has Substance P-like function in U-251 MG astrocytoma cells: a pharmacological and functional study. Berger A, Paige CJ. J Neuroimmunol. 2005;164(1-2):48-56. Termination of protease-activated receptor-1 signaling by beta-arrestins is independent of receptor phosphorylation. Chen CH, Paing MM, Trejo J. J Biol Chem. 2004;279(11):10020-31. Substance P in subtotal nephrectomy-salt hypertension. Katki KA, Supowit SC, Dipette DJ. Hypertension. 2002;39(2 Pt 2):389-93. Identification of receptors for neuromedin U and its role in feeding. Howard AD, Wang R, Pong SS, et al. Nature. 2000;406(6791):70-4. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is Substance P (Human, Rat, Mouse)?
Substance P (Human, Rat, Mouse) is a research peptide listed under catalog number 061-05 in the Substance P & Tachykinins family, human / mouse / rat sequence. It is supplied as 500 µg per unit for in vitro laboratory research.
What purity is listed for 061-05?
The imported catalog record lists ≥ 95% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should Substance P (Human, Rat, Mouse) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of Substance P (Human, Rat, Mouse)?
The 12-residue sequence is Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH2, molecular weight 1347.65.
What is the intended use of 061-05?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.