Research Peptides · Cat. 067-29
Irisin, recombinant (Human, Rat, Mouse, Canine)
Supplied as 10 µg per unit. Molecular weight 12.5 kDa. Species: Canine, Human, Mouse, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 067-29 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Irisin |
| Species | Canine, Human, Mouse, Rat |
| Unit size | 10 µg |
| Molecular weight | 12.5 kDa |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 10 µg of protein. Irisin is induced in renal ischemia-reperfusion to protect against tubular cell injury via suppressing p53. Liu Y, Fu Y, Liu Z, et al. Biochim Biophys Acta Mol Basis Dis. 2020;1866(7):165792. Recombinant Irisin Prevents the Reduction of Osteoblast Differentiation Induced by Stimulated Microgravity through Increasing β-Catenin Expression. Chen Z, Zhang Y, Zhao F, et al. Int J Mol Sci. 2020;21(4) Irisin reverses intestinal epithelial barrier dysfunction during intestinal injury via binding to the integrin αVβ5 receptor. Bi J, Zhang J, Ren Y, et al. J Cell Mol Med. 2020;24(1):996-1009. Irisin promotes proliferation but inhibits differentiation in osteoclast precursor cells. Ma Y, Qiao X, Zeng R, et al. FASEB J. 2018;:fj201700983RR . Effects and underlying mechanisms of irisin on the proliferation and apoptosis of pancreatic β cells. Liu S, Du F, Li X, et al. PLoS ONE. 2017;12(4):e0175498. Exercise-indusced irisin in bone and systemic irisin administration reveal new regulatory mechanisms of bone metabolism. Zhang J, Valverde P, Zhu X, et al. Bone Research. 2017;5:16056. Irisin Lowers Blood Pressure by Improvement of Endothelial Dysfunction via AMPK-Akt-eNOS-NO Pathway in the Spontaneously Hypertensive Rat. Fu J, Han Y, Wang J, et al. J Am Heart Assoc. 2016;5(11) FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle. Varela-rodríguez BM, Pena-bello L, Juiz-valiña P, Vidal-bretal B, Cordido F, Sangiao-alvarellos S. Sci Rep. 2016;6:29898. Irisin evokes bradycardia by activating cardiac-projecting neurons of nucleus ambiguus. Brailoiu E, Deliu E, Sporici RA, Brailoiu GC. Physiol Rep. 2015;3(6) Central and peripheral irisin differentially regulate blood pressure. Zhang W, Chang L, Zhang C, et al. Cardiovasc Drugs Ther. 2015;29(2):121-7. Irisin, a Novel Myokine, Regulates Glucose Uptake in Skeletal Muscle Cells via AMPK. Lee HJ, Lee JO, Kim N, et al. Mol Endocrinol. 2015;29(6):873-81. |
| · CAS | 9037-90-5 |
| CAS Number | 9037-90-5 |
| Solubility | Soluble in water (0.1-1.0 mg/ml). Then dilute with water or any desired aqueous buffer. |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Asp-Ser-Pro-Ser-Ala-Pro-Val-Asn-Val-Thr-Val-Arg-His-Leu-Lys-Ala-Asn-Ser-Ala-Val-Val-Ser-Trp-Asp-Val-Leu-Glu-Asp-Glu-Val-Val-Ile-Gly-Phe-Ala-Ile-Ser-Gln-Gln-Lys-Lys-Asp-Val-Arg-Met-Leu-Arg-Phe-Ile-Gln-Glu-Val-Asn-Thr-Thr-Thr-Arg-Ser-Cys-Ala-Leu-Trp-Asp-Leu-Glu-Glu-Asp-Thr-Glu-Tyr-Ile-Val-His-Val-Gln-Ala-Ile-Ser-Ile-Gln-Gly-Gln-Ser-Pro-Ala-Ser-Glu-Pro-Val-Leu-Phe-Lys-Thr-Pro-Arg-Glu-Ala-Glu-Lys-Met-Ala-Ser-Lys-Asn-Lys-Asp-Glu-Val-Thr-Met-Lys-Glu
Storage & handling
Store in dried form at -80°C for up to 3 months. For best results, rehydrate just before use. After rehydration, keep at +4°C for 1 week or at -80°C for longer-term storage. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is Irisin, recombinant (Human, Rat, Mouse, Canine)?
How should Irisin, recombinant (Human, Rat, Mouse, Canine) be stored?
What is the sequence of Irisin, recombinant (Human, Rat, Mouse, Canine)?
What is the intended use of 067-29?
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.