ELISA / EIA / RIA Kits · ELISA / EIA kit · Cat. EK-067-29
Irisin, recombinant (Human, Rat, Mouse, Canine) – ELISA Kit
Supplied as 96 wells per unit. Species: Canine, Human, Mouse, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | EK-067-29 |
|---|---|
| Product type | ELISA / EIA / RIA Kits · ELISA / EIA kit |
| Peptide family | Irisin |
| Species | Canine, Human, Mouse, Rat |
| Unit size | 96 wells |
| Sensitivity | 1.29 ng/ml |
| Specificity | Peptide % Irisin, Recombinant (Human, Rat, Mouse, Canine) 100 Irisin (1-112) (Human, Rat, Mouse, Canine) 100 FNDC5, isoform 4 recombinant (Human, Rat, Mouse, Canine) 9 Irisin precursor, C-terminal 48mer / FNDC5 (165-212) (Human) / FNDC5(162-209) (Rat, Mouse) 0 Irisin (42-95) (Human, Rat, Mouse, Canine) 0 FNDC4 (47-101) (Human) / FNDC4 (43-97) (Mouse) 0 FNDC4 (103-158) (Human) / FNDC4 (99-154) (Mouse) 0 FNDC4 / FRCP1 (190-234) (Human) 0 |
| Linear Range | 1.29 - 27.5 ng/ml |
| Inter-Assay CV | <15% |
| Intra-Assay CV | <10% |
| Standard Curve | Cerebrospinal fluid irisin correlates with amyloid-β, BDNF, and cognition in Alzheimer's disease. Lourenco MV, Ribeiro FC, Sudo FK, et al. Alzheimers Dement (Amst). 2020;12(1):e12034. A Polymorphism in the Irisin-encoding Gene (FNDC5) Associates With Hepatic Steatosis by Differential miRNA Binding to the 3'UTR Metwally M, Bayoumi A, Romero-gomez M, et al. Journal of Hepatology 2019;70(3):494-500. Circulating irisin levels in heart failure with preserved or reduced ejection fraction: A pilot study. Silvestrini A, Bruno C, Vergani E, et al. PLoS ONE. 2019;14(1):e0210320. Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models. Lourenco MV, Frozza RL, De freitas GB, et al. Nat Med. 2019;25(1):165-175. Association of serum concentrations of irisin and the adipokines adiponectin and leptin with epicardial fat in cardiovascular surgery patients. Kaneda H, Nakajima T, Haruyama A, et al. PLoS ONE. 2018;13(8):e0201499. Irisin Maternal Plasma and Cord Blood Levels in Mothers with Spontaneous Preterm and Term Delivery. Pavlova T, Zlamal F, Tomandl J, Hodicka Z, Gulati S, Bienertova-vasku J. Dis Markers. 2018;2018:7628957. Does high intensity exercise affects irisin plasma levels in hemodialysis patients? A pilot study. Esgalhado MGBM, Stockler-pinto MB, Cardozo LFMF, Barboza JE, Mafra D. J Bras Nefrol. 2018;40(1):53-58. Retinoic Acid Increases Fatty Acid Oxidation and Irisin Expression in Skeletal Muscle Cells and Impacts Irisin In Vivo. Amengual J, García-carrizo FJ, Arreguín A, et al. Cell Physiol Biochem. 2018;46(1):187-202. Lower Serum Irisin Levels Are Associated with Increased Vascular Calcification in Hemodialysis Patients. He L, He WY, A LT, Yang WL, Zhang AH. Kidney Blood Press Res. 2018;43(1):287-295. Exercise-induced irisin release as a determinant of the metabolic response to exercise training in obese youth: the EXIT trial. Devin R. Blizzard LeBlanc, Brittany V. Rioux, Cody Pelech et al., Physiol Rep. 2017 Dec; 5(23): e13539. Serum fatty acid-binding protein 4 (FABP4) concentration is associated with insulin resistance in peripheral tissues, A clinical study. Nakamura R, Okura T, Fujioka Y, et al. PLoS ONE. 2017;12(6):e0179737. Serum irisin levels correlated to peritoneal dialysis adequacy in nondiabetic peritoneal dialysis patients. Tan Z, Ye Z, Zhang J, et al. PLoS ONE. 2017;12(4):e0176137. Irisin: A Potential Link between Physical Exercise and Metabolism-An Observational Study in Differently Trained Subjects, from Elite Athletes to Sedentary People. Benedini S, Dozio E, Invernizzi PL, et al. J Diabetes Res. 2017;2017:1039161. Plasma Irisin Modestly Increases during Moderate and High-Intensity Afternoon Exercise in Obese Females. Winn NC, Grunewald ZI, Liu Y, Heden TD, Nyhoff LM, Kanaley JA. PLoS ONE. 2017;12(1):e0170690. Association of Serum Irisin Concentrations with Presence and Severity of Coronary Artery Disease. Deng W. Med Sci Monit. 2016;22:4193-4197. Effects of Body Weight Reduction on Serum Irisin and Metabolic Parameters in Obese Subjects. Fukushima Y, Kurose S, Shinno H, et al. Diabetes Metab J. 2016;40(5):386-395. Circulating Levels of Irisin in Hypopituitary and Normal Subjects. Pena-Bello L, Pértega-Diaz S, Sangiao-Alvarellos S, et al. Luque RM, ed. PLoS ONE. 2016;11(7):e0160364. High Serum Irisin Level as an Independent Predictor of Diabetes Mellitus: A Longitudinal Population-Based Study. Huh JH, Ahn SV, Choi JH, Koh SB, Chung CH. Medicine (Baltimore). 2016;95(23):e3742. Irisin Is Regulated by CAR in Liver and Is a Mediator of Hepatic Glucose and Lipid Metabolism. Mo L, Shen J, Liu Q, et al. Mol Endocrinol. 2016;30(5):533-42. Irisin modulates the association of interleukin-17A with the presence of non-proliferative diabetic retinopathy in patients with type 2 diabetes. Wang C, Wang L, Liu J, et al. Endocrine. 2016;53(2):459-64. Time-dependent irisin concentration changes in patients affected by overt hypothyroidism. Zybek-kocik A, Sawicka-gutaj N, Wrotkowska E, Sowi?ski J, Rucha?a M. Endokrynol Pol. 2016;67(5):476-480. Circulating Adipocyte Fatty Acid Binding Protein (FABP4) Levels Are Associated with Irisin in the Middle-Aged General Chinese Population. Zhang S, Yang L, Chen P, et al. PLoS ONE. 2016;11(1):e0146605. Effects and Molecular Mechanism of GST-Irisin on Lipolysis and Autocrine Function in 3T3-L1 Adipocytes. Gao S, Li F, Li H, Huang Y, Liu Y, Chen Y. PLoS ONE. 2016;11(1):e0147480. Irisin inhibits hepatic gluconeogenesis and increases glycogen synthesis via the PI3K/Akt pathway in type 2 diabetic mice and hepatocytes. Liu TY, Shi CX, Gao R, et al. Clin Sci. 2015;129(10):839-50. Betatrophin levels are increased in women with gestational diabetes mellitus compared to healthy pregnant controls. Ebert T, Kralisch S, Wurst U, et al. Eur J Endocrinol. 2015;173(1):1-7. Circulating irisin is lower in gestational diabetes mellitus. Zhao L, Li J, Li ZL, Yang J, Li ML, Wang GL. Endocr J. 2015;62(10):921-6. Irisin in blood increases transiently after single sessions of intense endurance exercise and heavy strength training. Nygaard H, Slettaløkken G, Vegge G, et al. PLoS ONE. 2015;10(3):e0121367. Associations of betatrophin levels with irisin in Chinese women with normal glucose tolerance. Xie X, Gao T, Yang M, et al. Diabetol Metab Syndr. 2015;7:26. Elevated circulating levels of irisin and the effect of metformin treatment in women with polycystic ovary syndrome. Li M, Yang M, Zhou X, et al. J Clin Endocrinol Metab. 2015;100(4):1485-93. Plasma irisin in runners and nonrunners: no favorable metabolic associations in humans. Hew-butler T, Landis-piwowar K, Byrd G, et al. Physiol Rep. 2015;3(1) Impact of supervised exercise rehabilitation on daily physical activity of cardiopulmonary patients. Ramadi A, Stickland MK, Rodgers WM, Haennel RG. Heart Lung. 2015;44(1):9-14. Complexity-Based Measures Inform Effects of Tai Chi Training on Standing Postural Control: Cross-Sectional and Randomized Trial Studies. Wayne PM, Gow BJ, Costa MD, et al. PLoS ONE. 2014;9(12):e114731. Thermogenic capacity is antagonistically regulated in classical brown and white subcutaneous fat depots by high fat diet and endurance training in rats: impact on whole-body energy expenditure. Wu MV, Bikopoulos G, Hung S, Ceddia RB. J Biol Chem. 2014;289(49):34129-40. Brown adipose tissue improves whole-body glucose homeostasis and insulin sensitivity in humans. Chondronikola M, Volpi E, Børsheim E, et al. Diabetes. 2014;63(12):4089-99. Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans. Lee P, Linderman JD, Smith S, et al. Cell Metab. 2014;19(2):302-9. The identification of irisin in human cerebrospinal fluid: influence of adiposity, metabolic markers, and gestational diabetes. Piya MK, Harte AL, Sivakumar K, et al. Am J Physiol Endocrinol Metab. 2014;306(5):E512-8. Serum levels of irisin in gestational diabetes mellitus during pregnancy and after delivery. Ebert T, Stepan H, Schrey S, et al. Cytokine. 2014;65(2):153-8. Plasma irisin depletion under energy restriction is associated with improvements in lipid profile in metabolic syndrome patients. De la iglesia R, Lopez-legarrea P, Crujeiras AB, et al. Clin Endocrinol (Oxf). 2014;81(2):306-11. Irisin and FNDC5 in retrospect: An exercise hormone or a transmembrane receptor?. Erickson HP. Adipocyte. 2013;2(4):289-93. Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs. Fain JN, Company JM, Booth FW, et al. Metab Clin Exp. 2013;62(10):1503-11. Resistance exercise training does not affect plasma irisin levels of hemodialysis patients. Moraes C, Leal VO, Marinho SM, et al. Horm Metab Res. 2013;45(12):900-4. Circulating irisin in relation to insulin resistance and the metabolic syndrome. Park KH, Zaichenko L, Brinkoetter M, et al. J Clin Endocrinol Metab. 2013;98(12):4899-907. Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies. Kurdiova T, Balaz M, Vician M, et al. J Physiol (Lond). 2014;592(5):1091-107. The effects of acute and chronic exercise on PGC-1α, irisin and browning of subcutaneous adipose tissue in humans. Norheim F, Langleite TM, Hjorth M, et al. FEBS J. 2014;281(3):739-49. |
| Sample Extraction | recommended |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Storage & handling
Store at 4°C
Frequently asked
What is Irisin, recombinant (Human, Rat, Mouse, Canine) – ELISA Kit?
Irisin, recombinant (Human, Rat, Mouse, Canine) – ELISA Kit is a elisa / eia kit elisa / eia / ria kit listed under catalog number EK-067-29 in the Irisin family, canine / human / mouse / rat sequence. It is supplied as 96 wells per unit for in vitro laboratory research.
How should Irisin, recombinant (Human, Rat, Mouse, Canine) – ELISA Kit be stored?
Store at 4°C
What is the intended use of EK-067-29?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.