Research Peptides · Cat. 031-31
Ghrelin (Rat, Mouse)
Supplied as 100 µg per unit. Purity ≥ 97%. Molecular weight 3314. Species: Mouse, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 031-31 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Ghrelin |
| Species | Mouse, Rat |
| Unit size | 100 µg |
| Molecular weight | 3314 Da |
| Purity | ≥ 97% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 100 µg of NET peptide. Deletion of ghrelin impairs neither growth nor appetite. Sun Y, Ahmed S, Smith RG. Mol Cell Biol. 2003;23(22):7973-81. Ghrelin attenuates intestinal ischemia/reperfusion injury in mice by activating the mTOR signaling pathway. Zhang H, Cui Z, Luo G, et al. Int J Mol Med. 2013;32(4):851-9. Clusterin and LRP2 are critical components of the hypothalamic feeding regulatory pathway. Gil SY, Youn BS, Byun K, et al. Nat Commun. 2013;4:1862. Effects of ghrelin on pulmonary NOD2 mRNA expression and NF-κB activation when protects against acute lung injury in rats challenged with cecal ligation and puncture. Peng Z, Zhu Y, Zhang Y, et al. Int Immunopharmacol. 2012;13(4):440-5. An age-dependent interaction with leptin unmasks ghrelin's bone-protective effects. Van der velde M, Van der eerden BC, Sun Y, et al. Endocrinology. 2012;153(8):3593-602. An acyl-ghrelin-specific neutralizing antibody inhibits the acute ghrelin-mediated orexigenic effects in mice. Lu SC, Xu J, Chinookoswong N, et al. Mol Pharmacol. 2009;75(4):901-7. Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. Liu J, Prudom CE, Nass R, et al. J Clin Endocrinol Metab. 2008;93(5):1980-7. B-type natriuretic peptide decreases gastric emptying and absorption. Addisu A, Gower WR, Landon CS, Dietz JR. Exp Biol Med (Maywood). 2008;233(4):475-82. Antiepileptic effects of ghrelin on pentylenetetrazole-induced seizures in rats. Obay BD, Tasdemir E, Tümer C, Bilgin HM, Sermet A. Peptides. 2007;28(6):1214-9. Effect of ghrelin administration on phagocytic activity in acute cold-restraint stress exposed rats. Tümer C, Bilgin HM, Obay BD, Diken H, Ta?demir E, Sermet A. Regul Pept. 2007;138(2-3):113-7. Peripheral ghrelin deepens torpor bouts in mice through the arcuate nucleus neuropeptide Y signaling pathway. Gluck EF, Stephens N, Swoap SJ. Am J Physiol Regul Integr Comp Physiol. 2006;291(5):R1303-9. Mice lacking ghrelin receptors resist the development of diet-induced obesity. Zigman JM, Nakano Y, Coppari R, et al. J Clin Invest. 2005;115(12):3564-72. The interoceptive cue properties of ghrelin generalize to cues produced by food deprivation. Davidson TL, Kanoski SE, Tracy AL, Walls EK, Clegg D, Benoit SC. Peptides. 2005;26(9):1602-10. Ghrelin stimulates proliferation and differentiation and inhibits apoptosis in osteoblastic MC3T3-E1 cells. Kim SW, Her SJ, Park SJ, et al. Bone. 2005;37(3):359-69. Presence and distribution of ghrelin-immunopositive cells in the chicken gastrointestinal tract. Neglia S, Arcamone N, Esposito V, Gargiulo G, De girolamo P. Acta Histochem. 2005;107(1):3-9. Ghrelin protects myocardium from isoproterenol-induced injury in rats. Chang L, Zhao J, Li GZ, et al. Acta Pharmacol Sin. 2004;25(9):1131-7. Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells. Li WG, Gavrila D, Liu X, et al. Circulation. 2004;109(18):2221-6. Therapeutic effects of ghrelin on endotoxic shock in rats. Chang L, Zhao J, Yang J, Zhang Z, Du J, Tang C. Eur J Pharmacol. 2003;473(2-3):171-6. Acute central ghrelin and GH secretagogues induce feeding and activate brain appetite centers. Lawrence CB, Snape AC, Baudoin FM, Luckman SM. Endocrinology. 2002;143(1):155-62. Delay of intracellular calcium transients using a calcium chelator: application to high-throughput screening of the capsaicin receptor ion channel and G-protein-coupled receptors. Grant SK, Bansal A, Mitra A, et al. Anal Biochem. 2001;294(1):27-35. |
| · CAS | 258338-12-4 |
| CAS Number | 258338-12-4 |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Gly-Ser-Ser(Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is Ghrelin (Rat, Mouse)?
Ghrelin (Rat, Mouse) is a research peptide listed under catalog number 031-31 in the Ghrelin family, mouse / rat sequence. It is supplied as 100 µg per unit for in vitro laboratory research.
What purity is listed for 031-31?
The imported catalog record lists ≥ 97% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should Ghrelin (Rat, Mouse) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of Ghrelin (Rat, Mouse)?
The 27-residue sequence is Gly-Ser-Ser(Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg, molecular weight 3314.
What is the intended use of 031-31?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.