Research Peptides · Cat. 031-30
Ghrelin (Human)
Supplied as 100 µg per unit. Purity ≥ 96%. Molecular weight 3371.92. Species: Human. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 031-30 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Ghrelin |
| Species | Human |
| Unit size | 100 µg |
| Molecular weight | 3371.92 Da |
| Purity | ≥ 96% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 100 µg of NET peptide. Ghrelin contributes to protection of hepatocellular injury induced by ischaemia/reperfusion. Qin Y, Li Z, Wang Z, et al. Liver Int. 2014;34(4):567-75. Ghrelin inhibits ovarian epithelial carcinoma cell proliferation in vitro. Xu Y, Pang X, Dong M, Wen F, Zhang Y. Oncol Rep. 2013;30(5):2063-70. Ghrelin inhibits high glucose-induced PC12 cell apoptosis by regulating TLR4/NF-κB pathway. Liu X, Xiao Q, Zhao K, Gao Y. Inflammation. 2013;36(6):1286-94. Ghrelin stimulates myogenic differentiation in a mouse muscle satellite cell line and in primary cultures of bovine myoblasts. Montoya-flores D, Mora O, Tamariz E, et al. J Anim Physiol Anim Nutr (Berl). 2012;96(4):725-38. Pharmacologic inhibition of ghrelin receptor signaling is insulin sparing and promotes insulin sensitivity. Longo KA, Govek EK, Nolan A, et al. J Pharmacol Exp Ther. 2011;339(1):115-24. Novel ghrelin assays provide evidence for independent regulation of ghrelin acylation and secretion in healthy young men. Liu J, Prudom CE, Nass R, et al. J Clin Endocrinol Metab. 2008;93(5):1980-7. Effect of ghrelin on human endothelial cells apoptosis induced by high glucose. Zhao H, Liu G, Wang Q, et al. Biochem Biophys Res Commun. 2007;362(3):677-81. The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor. Leung PK, Chow KB, Lau PN, et al. Cell Signal. 2007;19(5):1011-22. Adiponectin, ghrelin, and leptin differentially influence human platelet and human vascular endothelial cell functions: implication in obesity-associated cardiovascular diseases. Elbatarny HS, Netherton SJ, Ovens JD, Ferguson AV, Maurice DH. Eur J Pharmacol. 2007;558(1-3):7-13. Ghrelin inhibits proinflammatory responses and nuclear factor-kappaB activation in human endothelial cells. Li WG, Gavrila D, Liu X, et al. Circulation. 2004;109(18):2221-6. Response of circulating ghrelin levels to insulin therapy in children with newly diagnosed type 1 diabetes mellitus. Soriano-guillén L, Barrios V, Lechuga-sancho A, Chowen JA, Argente J. Pediatr Res. 2004;55(5):830-5. Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines. Cassoni P, Ghé C, Marrocco T, et al. Eur J Endocrinol. 2004;150(2):173-84. Ghrelin-induced GH secretion in domestic fowl in vivo and in vitro. Baudet ML, Harvey S. J Endocrinol. 2003;179(1):97-105. Neuromedin U is a potent agonist at the orphan G protein-coupled receptor FM3. Szekeres PG, Muir AI, Spinage LD, et al. J Biol Chem. 2000;275(27):20247-50. |
| · CAS | 258279-04-8 |
| CAS Number | 258279-04-8 |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Gly-Ser-Ser(Octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Arg-Val-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro-Arg
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is Ghrelin (Human)?
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This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.