All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy.
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Vasoactive intestinal peptide is a 28-amino-acid amidated peptide of the secretin/glucagon superfamily. It is encoded on the same precursor as peptide histidine methionine and signals through the class B receptors VPAC1 and VPAC2, which it shares with PACAP.
Why is VIP researched?
Studies examine its reported roles in smooth muscle relaxation, gastrointestinal secretion, enteric and central neurotransmission, circadian signalling in the suprachiasmatic nucleus, and modulation of immune cell responses in culture models.
What are PHM and PHI?
PHM (human) and PHI (other species) are peptides encoded on the same prepro-VIP precursor and released by processing. They are studied alongside VIP because precursor processing determines which peptides a given tissue actually produces.
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