Research Catalog · peptide family
TRPM8 Agonists — Research Products
2 catalog items
| Catalog # | Product | Type | Species | Size | Price | Add to cart |
|---|---|---|---|---|---|---|
| 014-51 | Cryosim-1 | Peptides | Other species | 5 mg | $194.00 | |
| 014-50 | Cryosim-3 / C3 (TRPM8 receptor agonist) | Peptides | Other species | 5 mg | $194.00 |
All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy. Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.
TRPM8 Agonists — frequently asked
What is TRPM8?
TRPM8 is a calcium-permeable, non-selective cation channel of the transient receptor potential melastatin family. It is described as the main cool temperature detector in primary sensory neurons and as the receptor activated by menthol and related cooling compounds.
What are Cryosim compounds?
Cryosim-1 and Cryosim-3 are synthetic cooling agents catalogued as TRPM8 agonists. They are small molecules rather than peptides, designed for selectivity over related channels such as TRPA1 and TRPV1 in pharmacological experiments.
How are TRPM8 agonists used in research?
They are applied in calcium imaging and electrophysiology using transfected cells or dissociated sensory neurons, in channel selectivity profiling, and in thermoreception, skin and ocular surface studies where cooling receptor activation is the experimental variable.