All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy.
Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.
Microtubule-Associated Protein Tau — frequently asked
What is protein tau?
Tau is an intrinsically disordered microtubule-associated protein encoded by MAPT. It is described as binding and stabilising axonal microtubules, and six isoforms are produced in adult human brain through alternative splicing of the transcript.
What is PHF6?
PHF6 is a hexapeptide motif, VQIVYK, within the microtubule-binding repeat region that is reported to be central to tau assembly into ordered filaments. Capped versions are widely used as minimal, tractable models of the aggregation process.
Why do tau residue numbers look unusually high?
Peptides are often numbered against the longest big tau sequence rather than a shorter brain isoform. Checking which numbering convention a product uses is important when comparing fragments across publications or supplier catalogues.
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