Research Catalog · peptide family
Opiorphin — Research Products
4 catalog items
| Catalog # | Product | Type | Species | Size | Price | Add to cart |
|---|---|---|---|---|---|---|
| 024-66 | [pGlu1]-Opiorphin (Human) | Peptides | Human | 500 µg | $73.00 | |
| 024-67 | [Tyr0]-Opiorphin (Human) | Peptides | Human | 500 µg | $104.00 | |
| T-024-67 | [Tyr0]-Opiorphin (Human) – I-125 Labeled I-125 labeled | Labeled Peptides | Human | 10 µCi | $1159.00 | |
| 024-65 | Opiorphin (Human) | Peptides | Human | 500 µg | $73.00 |
All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy. Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.
Opiorphin — frequently asked
What is opiorphin?
Opiorphin is the human salivary pentapeptide Gln-Arg-Phe-Ser-Arg, reported to be released from proline-rich protein 1. It is considered the human counterpart of the rat peptide sialorphin and is classed as an endogenous ectopeptidase inhibitor.
How does opiorphin act?
Published work describes inhibition of neprilysin and aminopeptidase N, the enzymes that degrade enkephalins. The peptide is therefore reported to act indirectly, by prolonging the local availability of endogenous opioid peptides rather than binding opioid receptors itself.
Why are modified analogs listed?
The pGlu-modified form reflects a cyclisation that N-terminal glutamine can undergo, while the Tyr-extended version adds a residue suitable for radioiodination. Both let researchers study stability, detection and tracer applications alongside the native sequence.