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INSL7 is another name for relaxin-3, a member of the insulin/relaxin superfamily. Like insulin it is described as a two-chain peptide joined by disulfide bonds, and it is studied mainly as a brain-expressed signalling peptide in rodent models.
Why are A-chain and B-chain peptides sold separately?
Two-chain peptides must be assembled from individual chains, so suppliers offer each chain independently. Protecting groups such as Acm or Bu on specific cysteines let researchers direct disulfide pairing step by step rather than relying on random oxidative folding.
Which receptors does relaxin-3 act on?
RXFP3 is generally described as its primary receptor, with reported binding also at RXFP4 and, more weakly, RXFP1. Because these receptors overlap in ligand recognition, selectivity profiling across the relaxin family receptor panel is common practice.
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