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Inotocin is the insect counterpart of the oxytocin and vasopressin peptides. It is a cyclic nonapeptide closed by a disulfide bridge with an amidated C-terminal tail, described in beetles such as Tribolium castaneum and other arthropod lineages.
Why is inotocin studied?
It provides a comparative anchor for the oxytocin/vasopressin superfamily, which is conserved across widely separated animal groups. Reported insect functions relate to water and ion balance, and its receptor is related to the vertebrate vasopressin receptor family.
What forms are available?
The native synthetic sequence is catalogued alongside the substituted [D-Arg8] analogue, which supports structure-activity comparison and stability work. As a synthetic invertebrate peptide, listings are defined by sequence rather than by a mammalian species designation.
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