Research Catalog · peptide family
Icilin — Research Products
1 catalog items
| Catalog # | Product | Type | Species | Size | Price | Add to cart |
|---|---|---|---|---|---|---|
| 050-53 | Icilin | Peptides | Other species | 1 mg | $217.00 |
All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy. Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.
Icilin — frequently asked
What is icilin?
Icilin is a synthetic small-molecule cooling agent rather than a peptide. It is included as a research tool compound for work on temperature-sensitive ion channels and is described as producing a cooling sensation far more potent than menthol.
Which channels does icilin act on?
It is generally described as an agonist at TRPM8, the cold and menthol-sensitive channel, with additional reported activity at TRPA1. This dual profile distinguishes it from menthol-type agonists that show greater selectivity for TRPM8 alone.
How is icilin used in research?
It serves as a reference agonist in calcium-imaging and patch-clamp assays, in receptor pharmacology screens, and in comparative studies with menthol and other TRP ligands. Reported calcium dependence also makes it useful for probing channel gating.