Research Catalog · peptide family
HMGI-C / HMGA2 — Research Products
4 catalog items
| Catalog # | Product | Type | Species | Size | Price | Add to cart |
|---|---|---|---|---|---|---|
| 004-11 | HMGIC (48-109) amide (Human) | Peptides | Human | 100 µg | $259.00 | |
| FG-004-11A | HMGIC (48-109) amide (Human) – FAM Labeled Fluorescent-labeled | Labeled Peptides | Human | 1 nmol | $409.00 | |
| 004-10 | HMGIC (76-109) amide (Human) | Peptides | Human | 100 µg | $179.00 | |
| WBK-004-10 | HMGIC (76-109) amide (Human) – Western Blot Kit Western blot kit | Assay Kits | Human | 1 kit | $832.00 |
All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy. Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.
HMGI-C / HMGA2 — frequently asked
What is HMGI-C?
HMGI-C, also called HMGA2, is a small high mobility group A chromatin protein. It binds AT-rich DNA through three AT-hook motifs and alters local DNA architecture, acting as an architectural factor rather than a conventional transcriptional activator.
Why is HMGA2 expression developmentally restricted?
Expression is high in embryonic tissue and falls sharply after development, largely through post-transcriptional repression by let-7 family microRNAs. This regulation is a frequent focus of studies on growth, body size and stem cell maintenance.
Which region do the peptides cover?
The listed (48-109) and (76-109) fragments correspond to the carboxy-terminal portion of the human protein rather than the AT-hook DNA-binding motifs. They are intended for antibody generation, blocking and detection rather than DNA-binding assays.