All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy.
Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.
Glypican-1 — frequently asked
What is glypican-1?
Glypican-1 is a heparan sulfate proteoglycan tethered to the outer face of the plasma membrane by a GPI anchor. Its heparan sulfate chains bind many extracellular ligands, so it is usually described as a co-receptor that modulates growth factor signalling.
What are prepro-glypican-1 peptides?
These are synthetic peptides matching defined residue ranges of the full human translation product, such as residues 24-68 or 121-176. They are chosen for antigenicity and used as immunogens, affinity ligands and blocking peptides in antibody work.
Do peptide antibodies detect the glycosaminoglycan chains?
No. Antibodies raised against synthetic core-protein peptides recognise the polypeptide sequence rather than the attached heparan sulfate chains. Studies concerned with glycosaminoglycan composition typically require enzymatic digestion or chain-specific reagents in addition to core protein antibodies.
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