Research Catalog · peptide family
Chromogranin (Granin Family) — Research Products
28 catalog items
All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy. Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.
Chromogranin (Granin Family) — frequently asked
What are chromogranins?
Chromogranins are acidic proteins stored in the dense-core secretory granules of neuroendocrine cells. Chromogranin A and B are the principal members, and both are processed at pairs of basic residues into numerous shorter peptides with separately reported activities.
Which peptides derive from chromogranin A?
Reported processing products include vasostatin-related sequences, chromofungin, pancreastatin, catestatin and several carboxy-terminal fragments. Which peptides predominate depends on the tissue and species, so catalogue entries specify both the parent protein and the residue range.
How are chromogranin reagents used?
They are used as immunogens and assay standards, as markers for identifying neuroendocrine cells in research samples, and as substrates or products in studies of prohormone convertase activity. Individual fragments are also tested directly in functional cell assays.