Peptide Medix product catalog

Support Contact
Peptide Medix
About Peptide Medix

Shipping options shown at checkout

Confirm cost and timing before payment

Research Catalog · peptide family

APP Intracellular Domain (AICD) — Research Products

6 catalog items

Catalog # Product Type Species Size Price Add to cart
018-70 APP Intracellular Domain (AICD) Long Form / Amyloid-beta Precursor (712-770) (Human) Peptides Human 100 µg $475.00 $559.00
B-018-70 APP Intracellular Domain (AICD) Long Form / Amyloid-beta Precursor (712-770) (Human) – Biotin Labeled Biotin-labeled Labeled Peptides Human 20 µg $612.00 $720.00
T-018-70 APP Intracellular Domain (AICD) Long Form / Amyloid-beta Precursor (712-770) (Human) – I-125 Labeled I-125 labeled Labeled Peptides Human 10 µCi $1159.00 $1364.00
018-69 APP Intracellular Domain (AICD) Short Form / Amyloid-beta Precursor (727-770) (Human) Peptides Human 100 µg $341.00 $402.00
B-018-69 APP Intracellular Domain (AICD) Short Form / Amyloid-beta Precursor (727-770) (Human) – Biotin Labeled Biotin-labeled Labeled Peptides Human 20 µg $475.00 $559.00
T-018-69 APP Intracellular Domain (AICD) Short Form / Amyloid-beta Precursor (727-770) (Human) – I-125 Labeled I-125 labeled Labeled Peptides Human 10 µCi $1159.00 $1364.00

All items are supplied for in vitro laboratory research use only — not for human or veterinary use, diagnosis or therapy. Prices are per unit as listed; each catalog number ships with its Certificate of Analysis.

APP Intracellular Domain (AICD) — frequently asked

What is the AICD?
The APP intracellular domain is the cytoplasmic fragment produced when gamma-secretase cleaves the amyloid-beta precursor protein within its membrane-spanning region. It is released into the cytosol by the same processing step that generates amyloid-beta peptides.
Why are long and short forms supplied?
Gamma-secretase cleaves at more than one position, giving cytoplasmic fragments of different lengths. Supplying both the (712-770) and (727-770) sequences lets researchers compare the reported forms in binding, stability and interaction experiments.
What is AICD used for in research?
It is used in pull-down assays with adaptor proteins such as Fe65, in studies of fragment degradation and stability, as an immunogen or blocking peptide, and as a reference standard when measuring gamma-secretase cleavage products.