Research Peptides · Cat. 002-26
DX 600, linear / ACE2-Specific Peptide Inhibitor
Supplied as 100 µg per unit. Purity ≥ 95%. Molecular weight 3076.38. Species: Other species. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 002-26 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Other Research Peptides |
| Species | Other species |
| Unit size | 100 µg |
| Molecular weight | 3076.38 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 100 µg of NET peptide. Angiotensin I is largely converted to angiotensin (1-7) and angiotensin (2-10) by isolated rat glomeruli. Velez JC, Ryan KJ, Harbeson CE, et al. Hypertension. 2009;53(5):790-7. Characterization of renin-angiotensin system enzyme activities in cultured mouse podocytes. Velez JC, Bland AM, Arthur JM, Raymond JR, Janech MG. Am J Physiol Renal Physiol. 2007;293(1):F398-407. Enalapril attenuates downregulation of Angiotensin-converting enzyme 2 in the late phase of ventricular dysfunction in myocardial infarcted rat. Ocaranza MP, Godoy I, Jalil JE, et al. Hypertension. 2006;48(4):572-8. ACE and ACE2 activity in diabetic mice. Wysocki J, Ye M, Soler MJ, et al. Diabetes. 2006;55(7):2132-9. Pseudotyped vesicular stomatitis virus for functional analysis of SARS coronavirus spike protein. Fukushi S, Mizutani T, Saijo M, et al. Adv Exp Med Biol. 2006;581:293-6. Vesicular stomatitis virus pseudotyped with severe acute respiratory syndrome coronavirus spike protein. Fukushi S, Mizutani T, Saijo M, et al. J Gen Virol. 2005;86(Pt 8):2269-74. The role of angiotensin converting enzyme 2 in the generation of angiotensin 1-7 by rat proximal tubules. Li N, Zimpelmann J, Cheng K, Wilkins JA, Burns KD. Am J Physiol Renal Physiol. 2005;288(2):F353-62. Novel peptide inhibitors of angiotensin-converting enzyme 2. Huang L, Sexton DJ, Skogerson K, et al. J Biol Chem. 2003;278(18):15532-40. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Ac-Gly-Asp-Tyr-Ser-His-Cys-Ser-Pro-Leu-Arg-Tyr-Tyr-Pro-Trp-Trp-Lys-Cys-Thr-Tyr-Pro-Asp-Pro-Glu-Gly-Gly-Gly-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
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This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.