Research Peptides · Cat. 019-06
Corticotropin Releasing Factor (CRF) (Human, Rat, Mouse, Canine, Feline)
Supplied as 200 µg per unit. Purity ≥ 95%. Molecular weight 4757.52. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 019-06 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Corticotropin & CRF Peptides |
| Unit size | 200 µg |
| Molecular weight | 4757.52 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 200 µg of NET peptide. Postnatal expression of corticotropin releasing factor (CRF) in rat urinary bladder. Laberge J, Malley SE, Girard B, Corrow K, Vizzard MA. Auton Neurosci. 2008;141(1-2):83-93. Characterization of CRF, AVT, and ACTH cDNA and pituitary-adrenal axis function in Japanese quail divergently selected for tonic immobility. Hazard D, Couty M, Guémené D. Am J Physiol Regul Integr Comp Physiol. 2007;293(3):R1421-9. Effects of in vivo and in vitro administration of ghrelin, leptin and neuropeptide mediators on pulsatile gonadotrophin-releasing hormone secretion from male rat hypothalamus before and after puberty. Lebrethon MC, Aganina A, Fournier M, Gérard A, Parent AS, Bourguignon JP. J Neuroendocrinol. 2007;19(3):181-8. Corticotropin-releasing hormone induces vascular endothelial growth factor release from human mast cells via the cAMP/protein kinase A/p38 mitogen-activated protein kinase pathway. Cao J, Cetrulo CL, Theoharides TC. Mol Pharmacol. 2006;69(3):998-1006. Differential regulation of corticotropin releasing factor 1alpha receptor endocytosis and trafficking by beta-arrestins and Rab GTPases. Holmes KD, Babwah AV, Dale LB, Poulter MO, Ferguson SS. J Neurochem. 2006;96(4):934-49. Urocortin 1 in the dorsal raphe regulates food and fluid consumption, but not ethanol preference in C57BL/6J mice. Weitemier AZ, Ryabinin AE. Neuroscience. 2006;137(4):1439-45. Neuropeptide W acts in brain to control prolactin, corticosterone, and growth hormone release. Baker JR, Cardinal K, Bober C, Taylor MM, Samson WK. Endocrinology. 2003;144(7):2816-21. The Edinger-Westphal-lateral septum urocortin pathway and its relationship to alcohol consumption. Bachtell RK, Weitemier AZ, Galvan-rosas A, et al. J Neurosci. 2003;23(6):2477-87. Hypocretin/orexin suppresses corticotroph responsiveness in vitro. Samson WK, Taylor MM. Am J Physiol Regul Integr Comp Physiol. 2001;281(4):R1140-5. Role of corticotrophin-releasing factor in effects of leptin on sympathetic nerve activity and arterial pressure. Correia ML, Morgan DA, Mitchell JL, Sivitz WI, Mark AL, Haynes WG. Hypertension. 2001;38(3):384-8. Feeding inhibition by urocortin in the rat hypothalamic paraventricular nucleus. Wang C, Mullet MA, Glass MJ, Billington CJ, Levine AS, Kotz CM. Am J Physiol Regul Integr Comp Physiol. 2001;280(2):R473-80. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is Corticotropin Releasing Factor (CRF) (Human, Rat, Mouse, Canine, Feline)?
Corticotropin Releasing Factor (CRF) (Human, Rat, Mouse, Canine, Feline) is a research peptide listed under catalog number 019-06 in the Corticotropin & CRF Peptides family. It is supplied as 200 µg per unit for in vitro laboratory research.
What purity is listed for 019-06?
The imported catalog record lists ≥ 95% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should Corticotropin Releasing Factor (CRF) (Human, Rat, Mouse, Canine, Feline) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of Corticotropin Releasing Factor (CRF) (Human, Rat, Mouse, Canine, Feline)?
The 42-residue sequence is Ser-Glu-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Met-Glu-Ile-Ile-NH2, molecular weight 4757.52.
What is the intended use of 019-06?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.