Research Peptides · Cat. 015-02
CGRP (Human)
Supplied as 200 µg per unit. Purity ≥ 95%. Molecular weight 3789.35. Species: Human. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 015-02 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Calcitonin Gene-Related Peptide (CGRP) |
| Species | Human |
| Unit size | 200 µg |
| Molecular weight | 3789.35 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 200 µg of NET peptide. |
| Solubility | Soluble in water |
| Disulfide Bridge | Disulfide bridge(s): Cys2-Cys7 Enhanced vascular responses to adrenomedullin in mice overexpressing receptor-activity-modifying protein 2. Tam CW, Husmann K, Clark NC, et al. Circ Res. 2006;98(2):262-70. Autocrine/paracrine role of inflammation-mediated calcitonin gene-related peptide and adrenomedullin expression in human adipose tissue. Linscheid P, Seboek D, Zulewski H, Keller U, Müller B. Endocrinology. 2005;146(6):2699-708. Stress-induced suppression of the gonadotropin-releasing hormone pulse generator in the female rat: a novel neural action for calcitonin gene-related peptide. Li XF, Bowe JE, Mitchell JC, Brain SD, Lightman SL, O'byrne KT. Endocrinology. 2004;145(4):1556-63. The assessment of vasoactive properties of CGRP and adrenomedullin in the microvasculature: a study using in vivo and in vitro assays in the mouse. Tam C, Brain SD. J Mol Neurosci. 2004;22(1-2):117-24. Autocrine role of adrenomedullin in the human adrenal cortex. Thomson LM, Kapas S, Carroll M, Hinson JP. J Endocrinol. 2001;170(1):259-65. Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners. Pio R, Martinez A, Unsworth EJ, et al. J Biol Chem. 2001;276(15):12292-300. Calcitonin gene-related peptide decreases expression of HLA-DR and CD86 by human dendritic cells and dampens dendritic cell-driven T cell-proliferative responses via the type I calcitonin gene-related peptide receptor. Carucci JA, Ignatius R, Wei Y, et al. J Immunol. 2000;164(7):3494-9. |
| Research topics | Cardiovascular Research |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Ala-Cys-Asp-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asn-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Lys-Ala-Phe-NH2
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is CGRP (Human)?
What purity is listed for 015-02?
How should CGRP (Human) be stored?
What is the sequence of CGRP (Human)?
What is the intended use of 015-02?
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.