Research Peptides · Cat. 003-62
CART (55-102) (Rat, Mouse, Bovine)
Supplied as 100 µg per unit. Purity ≥ 95%. Molecular weight 5259.26. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 003-62 |
|---|---|
| Product type | Research Peptides |
| Peptide family | CART (Cocaine- and Amphetamine-Regulated Transcript) |
| Unit size | 100 µg |
| Molecular weight | 5259.26 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 100 µg of NET peptide. |
| Solubility | Soluble in water |
| Disulfide Bridge | Disulfide bridge(s): Cys1-Cys3, Cys2-Cys5 & Cys4-Cys6 CART attenuates endoplasmic reticulum stress response induced by cerebral ischemia and reperfusion through upregulating BDNF synthesis and secretion. Qiu B, Hu S, Liu L, et al. Biochem Biophys Res Commun. 2013;436(4):655-9. Nicotine administration effects on feeding and cocaine-amphetamine-regulated transcript (CART) expression in the hypothalamus. Kramer PR, Kramer SF, Marr K, Guan G, Wellman PJ, Bellinger LL. Regul Pept. 2007;138(2-3):66-73. CART peptide promotes the survival of hippocampal neurons by upregulating brain-derived neurotrophic factor. Wu B, Hu S, Yang M, Pan H, Zhu S. Biochem Biophys Res Commun. 2006;347(3):656-61. Pituitary cocaine- and amphetamine-regulated transcript expression depends on the strain, sex and oestrous cycle in the rat. Kappeler L, Gautron L, Layé S, et al. J Neuroendocrinol. 2006;18(6):426-33. The premammillary hypothalamic area of the ewe: anatomical characterization of a melatonin target area mediating seasonal reproduction. Sliwowska JH, Billings HJ, Goodman RL, Coolen LM, Lehman MN. Biol Reprod. 2004;70(6):1768-75. Central pressor effects of CART peptides in anesthetized rats. Hwang LL, Chen CT, Li TL, Chiu CZ, Chi SF. Neuropeptides. 2004;38(2-3):69-76. Cocaine- and amphetamine-regulated transcript in the arcuate nucleus stimulates lipid metabolism to control body fat accrual on a high-fat diet. Wortley KE, Chang GQ, Davydova Z, Fried SK, Leibowitz SF. Regul Pept. 2004;117(2):89-99. Association of cocaine- and amphetamine-regulated transcript-immunoreactive elements with thyrotropin-releasing hormone-synthesizing neurons in the hypothalamic paraventricular nucleus and its role in the regulation of the hypothalamic-pituitary-thyroid axis during fasting. Fekete C, Mihály E, Luo LG, et al. J Neurosci. 2000;20(24):9224-34. Cocaine- and amphetamine-regulated transcript peptide in the rat epididymis: an immunohistochemical and electrophysiological study. Dun NJ, Dun SL, Wong PY, Yang J, Chang J. Biol Reprod. 2000;63(5):1518-24. Leptin increases serotonin turnover by inhibition of brain nitric oxide synthesis. Calapai G, Corica F, Corsonello A, et al. J Clin Invest. 1999;104(7):975-82. |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Ile-Pro-Ile-Tyr-Glu-Lys-Lys-Tyr-Gly-Gln-Val-Pro-Met-Cys-Asp-Ala-Gly-Glu-Gln-Cys-Ala-Val-Arg-Lys-Gly-Ala-Arg-Ile-Gly-Lys-Leu-Cys-Asp-Cys-Pro-Arg-Gly-Thr-Ser-Cys-Asn-Ser-Phe-Leu-Leu-Lys-Cys-Leu
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is CART (55-102) (Rat, Mouse, Bovine)?
What purity is listed for 003-62?
How should CART (55-102) (Rat, Mouse, Bovine) be stored?
What is the sequence of CART (55-102) (Rat, Mouse, Bovine)?
What is the intended use of 003-62?
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.