Research Peptides · Cat. 009-18
[D-Arg0, Hyp3, Thi5, D-Tic7, Oic8]-Bradykinin / HOE 140 / icatibant / JE-049
Supplied as 200 µg per unit. Purity ≥ 95%. Molecular weight 1305.67. Species: Human, Mouse, Rat. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 009-18 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Bradykinin & Kinins |
| Species | Human, Mouse, Rat |
| Unit size | 200 µg |
| Molecular weight | 1305.67 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 200 µg of NET peptide. Bradykinin B2 receptor knockout mice are protected from thrombosis by increased nitric oxide and prostacyclin. Shariat-Madar et al. Blood. 2006 Jul 1;108(1):192-9. Role of bradykinin B2-receptor in the sympathoadrenal effects of 'new pressor protein' related to human blood coagulation factor XII fragment. Amfilochiadis et al. J Hypertens. 2004 Jun;22(6):1173-81. Assembly and activation of HK-PK complex on endothelial cells results in bradykinin liberation and NO formation. Zhao et al. Am J Physiol Heart Circ Physiol 2001 Apr;280(4):H1821-9 B(1) and B(2) bradykinin receptors on adventitial fibroblasts of cerebral arteries are coupled to recombinant eNOS. Tsutsui M, Onoue H, Iida Y, Smith L, O'brien T, Katusic ZS. Am J Physiol Heart Circ Physiol. 2000;278(2):H367-72. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
D-Arg-Arg-Pro-Hyp-Gly-Thi-Ser-D-Tic-Oic-Arg
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is [D-Arg0, Hyp3, Thi5, D-Tic7, Oic8]-Bradykinin / HOE 140 / icatibant / JE-049?
What purity is listed for 009-18?
How should [D-Arg0, Hyp3, Thi5, D-Tic7, Oic8]-Bradykinin / HOE 140 / icatibant / JE-049 be stored?
What is the sequence of [D-Arg0, Hyp3, Thi5, D-Tic7, Oic8]-Bradykinin / HOE 140 / icatibant / JE-049?
What is the intended use of 009-18?
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.