Research Peptides · Cat. 005-06
ANP, alpha (1-28) (Human, Porcine, Ovine, Canine)
Supplied as 200 µg per unit. Purity ≥ 95%. Molecular weight 3078.44. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 005-06 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Atrial Natriuretic Peptide (ANP) |
| Unit size | 200 µg |
| Molecular weight | 3078.44 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 200 µg of NET peptide. |
| Solubility | Soluble in water |
| Disulfide Bridge | Disulfide bridge(s): Cys7-Cys23 PTHrP produced by myeloma plasma cells regulates their survival and pro-osteoclast activity for bone disease progression. Cafforio P, Savonarola A, Stucci S, et al. J Bone Miner Res. 2014;29(1):55-66. Cardiac hormones target nuclear oncogenes c-Fos and c-Jun in carcinoma cells. Manimala NJ, Frost CD, Lane ML, Higuera M, Beg R, Vesely DL. Eur J Clin Invest. 2013;43(11):1156-62. Endothelial permeability in vitro and in vivo: protective actions of ANP and omapatrilat in experimental atherosclerosis. Ichiki T, Izumi R, Cataliotti A, Larsen AM, Sandberg SM, Burnett JC. Peptides. 2013;48:21-6. Central role of β-catenin in anticancer effects of cardiac hormones. Skelton WP, Skelton M, Vesely DL. Anticancer Res. 2013;33(6):2409-14. Comparison of enzymatic recycling electrodes for measuring aminophenol: development of a highly sensitive natriuretic peptide assay system. Mie Y, Kowata K, Hirano Y, Niwa O, Mizutani F. Anal Sci. 2008;24(5):577-82. Four cardiac hormones eliminate 4-fold more human glioblastoma cells than the green mamba snake peptide. Vesely BA, Eichelbaum EJ, Alli AA, Sun Y, Gower WR, Vesely DL. Cancer Lett. 2007;254(1):94-101. Vessel dilator: most potent of the atrial natriuretic peptides in decreasing the number and DNA synthesis of human squamous lung cancer cells. Vesely BA, Fitz SR, Gower WR, Vesely DL. Cancer Lett. 2006;233(2):226-31. Five cardiac hormones decrease the number of human small-cell lung cancer cells. Vesely BA, Song S, Sanchez-ramos J, et al. Eur J Clin Invest. 2005;35(6):388-98. Endothelin inhibits NPR-A and stimulates eNOS gene expression in rat IMCD cells. Ye Q, Chen S, Gardner DG. Hypertension. 2003;41(3 Pt 2):675-81. Dendroaspis natriuretic peptide relaxes isolated human arteries and veins. Best PJ, Burnett JC, Wilson SH, Holmes DR, Lerman A. Cardiovasc Res. 2002;55(2):375-84. Divergent effects of ANP and BNP in acute heart failure: evidence for a putative BNP-selective receptor?. Brunner-la rocca HP, Woods RL, Kaye DM, et al. J Hypertens. 2002;20(6):1195-201. Renal responsiveness to aldosterone during exposure to simulated microgravity. Convertino VA, Luetkemeier MJ, Elliott JJ, Ludwig DA, Wade CE. J Appl Physiol. 2000;89(5):1737-43. Atrial, B-type, and C-type natriuretic peptides cause mesenteric vasoconstriction in conscious dogs. Woods RL, Jones MJ. Am J Physiol. 1999;276(5 Pt 2):R1443-52. |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is ANP, alpha (1-28) (Human, Porcine, Ovine, Canine)?
ANP, alpha (1-28) (Human, Porcine, Ovine, Canine) is a research peptide listed under catalog number 005-06 in the Atrial Natriuretic Peptide (ANP) family. It is supplied as 200 µg per unit for in vitro laboratory research.
What purity is listed for 005-06?
The imported catalog record lists ≥ 95% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should ANP, alpha (1-28) (Human, Porcine, Ovine, Canine) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of ANP, alpha (1-28) (Human, Porcine, Ovine, Canine)?
The 28-residue sequence is Ser-Leu-Arg-Arg-Ser-Ser-Cys-Phe-Gly-Gly-Arg-Met-Asp-Arg-Ile-Gly-Ala-Gln-Ser-Gly-Leu-Gly-Cys-Asn-Ser-Phe-Arg-Tyr, molecular weight 3078.44.
What is the intended use of 005-06?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.