Research Peptides · Cat. 002-12
Angiotensin II (Human, Rat, Mouse, Porcine, Canine, Guinea Pig, Rabbit)
Supplied as 5 mg per unit. Purity ≥ 95%. Molecular weight 1046.19. Technical values shown are imported catalog fields and should be confirmed against current documentation. Laboratory research use only.
Specifications
| Catalog number | 002-12 |
|---|---|
| Product type | Research Peptides |
| Peptide family | Angiotensin |
| Unit size | 5 mg |
| Molecular weight | 1046.19 Da |
| Purity | ≥ 95% |
| Validation | Exhibits correct molecular weight |
| Appearance | White powder |
| Contents | Each vial contains 5 mg of NET peptide. Angiotensin-[1-12] interacts with angiotensin type I receptors. Chan KH, Chen YH, Zhang Y, Wong YH, Dun NJ. Neuropharmacology. 2014;81:267-73. Endothelin ET(B) receptors contribute to sex differences in blood pressure elevation in angiotensin II hypertensive rats on a high-salt diet. Kittikulsuth W, Looney SW, Pollock DM. Clin Exp Pharmacol Physiol. 2013;40(6):362-70. Sexual dimorphism in urinary angiotensinogen excretion during chronic angiotensin II-salt hypertension. Rands VF, Seth DM, Kobori H, Prieto MC. Gend Med. 2012;9(4):207-18. Oxidative stress contributes to sex differences in angiotensin II-mediated hypertension in spontaneously hypertensive rats. Bhatia K, Elmarakby AA, El-remessy AB, El-remessey A, Sullivan JC. Am J Physiol Regul Integr Comp Physiol. 2012;302(2):R274-82. ETA activation mediates angiotensin II-induced infiltration of renal cortical T cells. Boesen EI, Krishnan KR, Pollock JS, Pollock DM. J Am Soc Nephrol. 2011;22(12):2187-92. Sex differences in renal medullary endothelin receptor function in angiotensin II hypertensive rats. Kittikulsuth W, Pollock JS, Pollock DM. Hypertension. 2011;58(2):212-8. Angiotensin II-induced vascular endothelial dysfunction through RhoA/Rho kinase/p38 mitogen-activated protein kinase/arginase pathway. Shatanawi A, Romero MJ, Iddings JA, et al. Am J Physiol, Cell Physiol. 2011;300(5):C1181-92. The renin-angiotensin system mediates hyperoxia-induced collagen production in human lung fibroblasts. Lang YD, Hung CL, Wu TY, Wang LF, Chen CM. Free Radic Biol Med. 2010;49(1):88-95. Early life stress sensitizes rats to angiotensin II-induced hypertension and vascular inflammation in adult life. Loria AS, Pollock DM, Pollock JS. Hypertension. 2010;55(2):494-9. Enhanced Distal Nephron Sodium Reabsorption in Chronic Angiotensin II Infused Mice. Zhao D, Seth DM, Navar LG. Hypertension. 2009;54(1):120-126. Intact renal afferent arteriolar autoregulatory responsiveness in db/db mice. Park S, Bivona BJ, Feng Y, Lazartigues E, Harrison-bernard LM. Am J Physiol Renal Physiol. 2008;295(5):F1504-11. Secreted protein acidic and rich in cysteine deficiency ameliorates renal inflammation and fibrosis in angiotensin hypertension. Socha MJ, Manhiani M, Said N, Imig JD, Motamed K. Am J Pathol. 2007;171(4):1104-12. Compromised renal microvascular reactivity of angiotensin type 1 double null mice. Park S, Bivona BJ, Harrison-bernard LM. Am J Physiol Renal Physiol. 2007;293(1):F60-7. Aldosterone receptor antagonism exacerbates intrarenal angiotensin II augmentation in ANG II-dependent hypertension. Ortiz RM, Graciano ML, Seth D, Awayda MS, Navar LG. Am J Physiol Renal Physiol. 2007;293(1):F139-47. Interleukin-10 counteracts impaired endothelium-dependent relaxation induced by ANG II in murine aortic rings. Zemse SM, Hilgers RH, Webb RC. Am J Physiol Heart Circ Physiol. 2007;292(6):H3103-8. Novel nitric oxide synthase--dependent mechanism of vasorelaxation in small arteries from hypertensive rats. Kang KT, Sullivan JC, Sasser JM, Imig JD, Pollock JS. Hypertension. 2007;49(4):893-901. Synergistic actions of enalapril and tempol during chronic angiotensin II-induced hypertension. Elmarakby AA, Williams JM, Imig JD, Pollock JS, Pollock DM. Vascul Pharmacol. 2007;46(2):144-51. Angiotensin II activates a nitric-oxide-driven inhibitory feedback in the rat paraventricular nucleus. Latchford KJ, Ferguson AV. J Neurophysiol. 2003;89(3):1238-44. Ex vivo antisense oligonucleotides to proliferating cell nuclear antigen and Cdc2 kinase inhibit graft coronary artery disease. Miniati DN, Hoyt EG, Feeley BT, Poston RS, Robbins RC. Circulation. 2000;102(19 Suppl 3):III237-42. |
| Solubility | Soluble in water |
| Intended use | In vitro laboratory research only — not for human or veterinary use, diagnostic or therapeutic purposes |
Sequence
Asp-Arg-Val-Tyr-Ile-His-Pro-Phe
Storage & handling
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
Confirm handling and preparation requirements against current product documentation and the requirements of your laboratory protocol.
Frequently asked
What is Angiotensin II (Human, Rat, Mouse, Porcine, Canine, Guinea Pig, Rabbit)?
Angiotensin II (Human, Rat, Mouse, Porcine, Canine, Guinea Pig, Rabbit) is a research peptide listed under catalog number 002-12 in the Angiotensin family. It is supplied as 5 mg per unit for in vitro laboratory research.
What purity is listed for 002-12?
The imported catalog record lists ≥ 95% (exhibits correct molecular weight). Request and verify current lot-specific documentation before purchase.
How should Angiotensin II (Human, Rat, Mouse, Porcine, Canine, Guinea Pig, Rabbit) be stored?
Up to 6 months in lyophilized form at 0-5°C. For best results, rehydrate just before use. After rehydration, keep solution at +4°C for up to 5 days or freeze at -20°C for up to 3 months. Aliquot before freezing to avoid repeated freeze-thaw cycles.
What is the sequence of Angiotensin II (Human, Rat, Mouse, Porcine, Canine, Guinea Pig, Rabbit)?
The 8-residue sequence is Asp-Arg-Val-Tyr-Ile-His-Pro-Phe, molecular weight 1046.19.
What is the intended use of 002-12?
This catalog listing is for laboratory research use only. It is not represented as a drug, food, supplement, cosmetic or diagnostic product, and it is not offered for human or veterinary use.
This page reproduces an imported research-catalog record. Verify identity, specifications, documentation and suitability before purchase. The item is offered only for laboratory research and is not represented for human or veterinary use.